Drone warfare is a huge part of the Ukraine and Russian war. F-16s have been operating in Ukraine for a while now but here is an article about them intercepting and shooting down an unspecified target. Really interesting to see in action.

http://www.newsweek.com/ukraine-f16-fighter-jets-russia-combat-footage-2066659

newsweek.com

Ukraine's F-16 combat jet intercepts aerial target in rare footage

Kyiv confirmed in early August last year it had received the first batch of its donated F-16s.